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The three faces of vestibular ganglionitis.

TitleThe three faces of vestibular ganglionitis.
Publication TypeJournal Article
Year of Publication2002
AuthorsGacek RR, Gacek MR
JournalAnn Otol Rhinol Laryngol
Date Published2002 Feb
KeywordsAdult, Aged, Aged, 80 and over, Facial Nerve, Female, Ganglia, Sensory, Geniculate Ganglion, Herpes Simplex, Herpes Zoster, Humans, Male, Meniere Disease, Middle Aged, Recurrence, Satellite Cells, Perineuronal, Temporal Bone, Vertigo, Vestibular Neuronitis

<p>We present temporal bone and clinical evidence that common syndromes of recurrent vertigo are caused by a viral infection of the vestibular ganglion. In the present series, histopathologic and radiologic changes in the vestibular ganglion and meatal ganglion were consistent with a viral inflammation of ganglion cells in cases of Meniere's disease, benign paroxysmal positional vertigo, and vestibular neuronitis. Clinical observations of multiple neuropathies involving cranial nerves V, VII, and VIII on the same side in patients with recurrent vertigo are best explained by a cranial polyganglionitis caused by a neurotrophic virus, which is reactivated by a stressful event later in life. The reactivation of the latent virus may manifest as one of the above vertigo syndromes, depending on the part of the vestibular ganglion that is inflamed, the type and strain of the virus, and host resistance.</p>

Alternate JournalAnn. Otol. Rhinol. Laryngol.
Citation KeyCK60
PubMed ID11860061