Arbusow, V; Strupp, M; Wasicky, R; Horn, A K; Schulz, P; Brandt, T

Detection of herpes simplex virus type 1 in human vestibular nuclei. Journal Article

Neurology, 55 , pp. 880-2, 2000, ISSN: 0028-3878.

Abstract | BibTeX

Abstract

The distribution of herpes simplex virus type 1 (HSV-1) in human geniculate, vestibular ganglia, and vestibular nuclei was determined in 10 human temporal bones and brainstems of five individuals by PCR. HSV-1 was found in 3 of 10 of each ganglia and vestibular nuclei. The various patterns of HSV-1 infection of vestibular structures are compatible with virus migration from the vestibular ganglia to the vestibular nuclei and from the ipsilateral to the contralateral vestibular nucleus via commissural fibers.